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Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo
Glucocorticoid-induced osteoporosis is a frequent complication of systemic glucocorticoid (GC) therapy and mainly characterized by suppressed osteoblast activity. Wnt16 derived from osteogenic cells is a key determinant of bone mass. Here, we assessed whether GC suppress bone formation via inhibitin...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5992207/ https://ncbi.nlm.nih.gov/pubmed/29880826 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26300-z |
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