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Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH

Although recent evidence suggests the involvement of iron accumulation in the pathogenesis of nonalcoholic steatohepatitis (NASH), the underlying mechanisms remain poorly understood. Previously, we reported a unique histological structure termed “crown-like structure (CLS),” where liver-resident mac...

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Enregistré dans:
Détails bibliographiques
Publié dans:iScience
Auteurs principaux: Kanamori, Yohei, Tanaka, Miyako, Itoh, Michiko, Ochi, Kozue, Ito, Ayaka, Hidaka, Isao, Sakaida, Isao, Ogawa, Yoshihiro, Suganami, Takayoshi
Format: Artigo
Langue:Inglês
Publié: Elsevier 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820131/
https://ncbi.nlm.nih.gov/pubmed/33521599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.102032
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