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Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH

Although recent evidence suggests the involvement of iron accumulation in the pathogenesis of nonalcoholic steatohepatitis (NASH), the underlying mechanisms remain poorly understood. Previously, we reported a unique histological structure termed “crown-like structure (CLS),” where liver-resident mac...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Kanamori, Yohei, Tanaka, Miyako, Itoh, Michiko, Ochi, Kozue, Ito, Ayaka, Hidaka, Isao, Sakaida, Isao, Ogawa, Yoshihiro, Suganami, Takayoshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820131/
https://ncbi.nlm.nih.gov/pubmed/33521599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.102032
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