Iron-rich Kupffer cells exhibit phenotypic changes during the development of liver fibrosis in NASH

Although recent evidence suggests the involvement of iron accumulation in the pathogenesis of nonalcoholic steatohepatitis (NASH), the underlying mechanisms remain poorly understood. Previously, we reported a unique histological structure termed “crown-like structure (CLS),” where liver-resident mac...

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Bibliografske podrobnosti
izdano v:iScience
Main Authors: Kanamori, Yohei, Tanaka, Miyako, Itoh, Michiko, Ochi, Kozue, Ito, Ayaka, Hidaka, Isao, Sakaida, Isao, Ogawa, Yoshihiro, Suganami, Takayoshi
Format: Artigo
Jezik:Inglês
Izdano: Elsevier 2021
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7820131/
https://ncbi.nlm.nih.gov/pubmed/33521599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.102032
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