Melanocortin 4 Receptor–Deficient Mice as a Novel Mouse Model of Nonalcoholic Steatohepatitis

Obesity may be viewed as a state of chronic low-grade inflammation that participates in the development of the metabolic syndrome. Nonalcoholic steatohepatitis (NASH) is considered a hepatic phenotype of the metabolic syndrome and a high risk for progression to cirrhosis and hepatocellular carcinoma...

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Hlavní autoři: Itoh, Michiko, Suganami, Takayoshi, Nakagawa, Nobutaka, Tanaka, Miyako, Yamamoto, Yukio, Kamei, Yasutomi, Terai, Shuji, Sakaida, Isao, Ogawa, Yoshihiro
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2011
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3204024/
https://ncbi.nlm.nih.gov/pubmed/21906580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2011.07.014
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