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Telmisartan improves nonalcoholic steatohepatitis in medaka (Oryzias latipes) by reducing macrophage infiltration and fat accumulation

We investigated the efficacy of the antihypertensive drug telmisartan (Tel) and the mechanisms underlying the progression from simple steatosis to nonalcoholic steatohepatitis (NASH) in a medaka (Oryzias latipes) NASH model. We used the NASH activity score (NAS) developed in humans to assess the his...

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Detalhes bibliográficos
Main Authors: Kuwashiro, Shinya, Terai, Shuji, Oishi, Toshiyuki, Fujisawa, Koichi, Matsumoto, Toshihiko, Nishina, Hiroshi, Sakaida, Isao
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063342/
https://ncbi.nlm.nih.gov/pubmed/21327395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-011-1132-7
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