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Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age
Cardiac fibrosis is a pathophysiologic hallmark of the aging heart, but little is known about how fibroblast proliferation and transcriptional programs change throughout the life span of the organism. Using EdU pulse labeling, we demonstrated that more than 50% of cardiac fibroblasts were actively p...
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| Publié dans: | JCI Insight |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7819745/ https://ncbi.nlm.nih.gov/pubmed/33180747 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140628 |
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