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Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age

Cardiac fibrosis is a pathophysiologic hallmark of the aging heart, but little is known about how fibroblast proliferation and transcriptional programs change throughout the life span of the organism. Using EdU pulse labeling, we demonstrated that more than 50% of cardiac fibroblasts were actively p...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:JCI Insight
Egile Nagusiak: Wu, Rimao, Ma, Feiyang, Tosevska, Anela, Farrell, Colin, Pellegrini, Matteo, Deb, Arjun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819745/
https://ncbi.nlm.nih.gov/pubmed/33180747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140628
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