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Cardiac fibroblast proliferation rates and collagen expression mature early and are unaltered with advancing age

Cardiac fibrosis is a pathophysiologic hallmark of the aging heart, but little is known about how fibroblast proliferation and transcriptional programs change throughout the life span of the organism. Using EdU pulse labeling, we demonstrated that more than 50% of cardiac fibroblasts were actively p...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:JCI Insight
Κύριοι συγγραφείς: Wu, Rimao, Ma, Feiyang, Tosevska, Anela, Farrell, Colin, Pellegrini, Matteo, Deb, Arjun
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Clinical Investigation 2020
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819745/
https://ncbi.nlm.nih.gov/pubmed/33180747
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.140628
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