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Canine orosomucoid (alpha-1 acid glycoprotein) variants and their influence on drug plasma protein binding

Orosomucoid polymorphisms influence plasma drug binding in humans, however, canine variants and their effect on drug plasma protein binding has not yet been reported. In this study, the orosomucoid gene (ORM1) was sequenced in 100 dogs to identify the most common variant and its allele frequency det...

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Dades bibliogràfiques
Publicat a:J Vet Pharmacol Ther
Autors principals: Costa, Ana P., Court, Michael H., Villarino, Nicolas F., Burke, Neal S., Mealey, Katrina L.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7819641/
https://ncbi.nlm.nih.gov/pubmed/32744755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jvp.12899
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