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pH-dependence of warfarin binding to alpha 1-acid glycoprotein (orosomucoid).

The binding of warfarin to alpha 1-acid glycoprotein (AAG) was found to increase with decreasing pH. The u.v.-visible difference spectra generated upon binding to AAG at pH 5.0 or 7.4 showed warfarin to bind as the anion. Warfarin-binding data were satisfactorily fitted to a model that incorporates...

詳細記述

保存先:
書誌詳細
主要な著者: Urien, S, Brée, F, Testa, B, Tillement, J P
フォーマット: Artigo
言語:Inglês
出版事項: 1993
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC1132241/
https://ncbi.nlm.nih.gov/pubmed/8435073
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