Nalaganje...
Canine Albumin Polymorphisms and Their Impact on Drug Plasma Protein Binding
Drug binding to plasma proteins is routinely determined during drug development. Albumin polymorphisms c.1075G>T (p.Ala359Ser) and c.1422A>T (p.Glu474Asp) were previously shown to alter plasma protein binding of a drug candidate (D01-4582, 4-[1-[3-chloro-4-[N′-(2-methylphenyl)ureido]phenylacet...
Shranjeno v:
| izdano v: | Drug Metab Dispos |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The American Society for Pharmacology and Experimental Therapeutics
2019
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6744390/ https://ncbi.nlm.nih.gov/pubmed/31481400 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.119.087304 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|