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PDGFRβ is an essential therapeutic target for BRCA1-deficient mammary tumors
BACKGROUND: Basal-like breast cancers (BLBCs) are a leading cause of cancer death due to their capacity to metastasize and lack of effective therapies. More than half of BLBCs have a dysfunctional BRCA1. Although most BRCA1-deficient cancers respond to DNA-damaging agents, resistance and tumor recur...
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| Publicado no: | Breast Cancer Res |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7819225/ https://ncbi.nlm.nih.gov/pubmed/33478572 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13058-021-01387-x |
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