p16 loss rescues functional decline of Brca1-deficient mammary stem cells

Recent evidence indicates that the accumulation of endogenous DNA damage can induce senescence and limit the function of adult stem cells. It remains elusive whether deficiency in DNA damage repair is associated with the functional alteration of mammary stem cells. In this article, we reported that...

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Publicat a:Cell Cycle
Autors principals: Scott, Alexandria, Bai, Feng, Chan, Ho Lam, Liu, Shiqin, Slingerland, Joyce M., Robbins, David J., Capobianco, Anthony J., Pei, Xin-Hai
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2017
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405722/
https://ncbi.nlm.nih.gov/pubmed/28278054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1295185
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