p16 loss rescues functional decline of Brca1-deficient mammary stem cells

Recent evidence indicates that the accumulation of endogenous DNA damage can induce senescence and limit the function of adult stem cells. It remains elusive whether deficiency in DNA damage repair is associated with the functional alteration of mammary stem cells. In this article, we reported that...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Scott, Alexandria, Bai, Feng, Chan, Ho Lam, Liu, Shiqin, Slingerland, Joyce M., Robbins, David J., Capobianco, Anthony J., Pei, Xin-Hai
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405722/
https://ncbi.nlm.nih.gov/pubmed/28278054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2017.1295185
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