Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β

BACKGROUND: Metastatic breast cancer is a leading cause of cancer-related death in women worldwide. Infusion of natural killer (NK) cells is an emerging immunotherapy for such malignant tumors, although elimination of the immunosuppressive tumor environment is required to improve its efficacy. The e...

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Bibliografiske detaljer
Udgivet i:J Immunother Cancer
Main Authors: Brownlie, Demi, Doughty-Shenton, Dahlia, YH Soong, Daniel, Nixon, Colin, O Carragher, Neil, M Carlin, Leo, Kitamura, Takanori
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2021
Fag:
Immune Cell Therapies and Immune Cell Engineering
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818844/
https://ncbi.nlm.nih.gov/pubmed/33472858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001740
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