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Purification of Recombinant α-synuclein: A Comparison of Commonly Used Protocols

[Image: see text] The initial state of the intrinsically disordered protein α-synuclein (aSyn), e.g., the presence of oligomers and degradation products, or the presence of contaminants and adducts can greatly influence the aggregation kinetics and toxicity of the protein. Here, we compare four comm...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Stephens, Amberley D., Matak-Vinkovic, Dijana, Fernandez-Villegas, Ana, Kaminski Schierle, Gabriele S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7818547/
https://ncbi.nlm.nih.gov/pubmed/33237763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00725
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