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Different Structural Conformers of Monomeric α-Synuclein Identified after Lyophilizing and Freezing

[Image: see text] Understanding the mechanisms behind amyloid protein aggregation in diseases, such as Parkinson’s and Alzheimer’s disease, is often hampered by the reproducibility of in vitro assays. Yet, understanding the basic mechanisms of protein misfolding is essential for the development of n...

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Detalhes bibliográficos
Publicado no:Anal Chem
Main Authors: Stephens, Amberley D., Nespovitaya, Nadezhda, Zacharopoulou, Maria, Kaminski, Clemens F., Phillips, Jonathan J., Kaminski Schierle, Gabriele S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2018
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6047843/
https://ncbi.nlm.nih.gov/pubmed/29750859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.analchem.8b01264
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