Mebendazole and temozolomide in patients with newly diagnosed high-grade gliomas: results of a phase 1 clinical trial

BACKGROUND: Mebendazole is an anthelmintic drug introduced for human use in 1971 that extends survival in preclinical models of glioblastoma and other brain cancers. METHODS: A single-center dose-escalation and safety study of mebendazole in 24 patients with newly diagnosed high-grade gliomas in com...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neurooncol Adv
Main Authors: Gallia, Gary L, Holdhoff, Matthias, Brem, Henry, Joshi, Avadhut D, Hann, Christine L, Bai, Ren-Yuan, Staedtke, Verena, Blakeley, Jaishri O, Sengupta, Soma, Jarrell, T Che, Wollett, Jessica, Szajna, Kelly, Helie, Nicole, Mattox, Austin K, Ye, Xiaobu, Rudek, Michelle A, Riggins, Gregory J
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817892/
https://ncbi.nlm.nih.gov/pubmed/33506200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/noajnl/vdaa154
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados