Structural and molecular basis of cross-seeding barriers in amyloids

Neurodegenerative disorders are frequently associated with β-sheet-rich amyloid deposits. Amyloid-forming proteins can aggregate under different structural conformations known as strains, which can exhibit a prion-like behavior and distinct pathophenotypes. Precise molecular determinants defining st...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Daskalov, Asen, Martinez, Denis, Coustou, Virginie, El Mammeri, Nadia, Berbon, Mélanie, Andreas, Loren B., Bardiaux, Benjamin, Stanek, Jan, Noubhani, Abdelmajid, Kauffmann, Brice, Wall, Joseph S., Pintacuda, Guido, Saupe, Sven J., Habenstein, Birgit, Loquet, Antoine
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817211/
https://ncbi.nlm.nih.gov/pubmed/33443172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014085118
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