Signal Transduction by a Fungal NOD-Like Receptor Based on Propagation of a Prion Amyloid Fold

In the fungus Podospora anserina, the [Het-s] prion induces programmed cell death by activating the HET-S pore-forming protein. The HET-s β-solenoid prion fold serves as a template for converting the HET-S prion-forming domain into the same fold. This conversion, in turn, activates the HET-S pore-fo...

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Publicado en:PLoS Biol
Autores principales: Daskalov, Asen, Habenstein, Birgit, Martinez, Denis, Debets, Alfons J. M., Sabaté, Raimon, Loquet, Antoine, Saupe, Sven J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4344463/
https://ncbi.nlm.nih.gov/pubmed/25671553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002059
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