Identification of a novel cell death-inducing domain reveals that fungal amyloid-controlled programmed cell death is related to necroptosis

Recent findings have revealed the role of prion-like mechanisms in the control of host defense and programmed cell death cascades. In fungi, HET-S, a cell death-inducing protein containing a HeLo pore-forming domain, is activated through amyloid templating by a Nod-like receptor (NLR). Here we chara...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Daskalov, Asen, Habenstein, Birgit, Sabaté, Raimon, Berbon, Mélanie, Martinez, Denis, Chaignepain, Stéphane, Coulary-Salin, Bénédicte, Hofmann, Kay, Loquet, Antoine, Saupe, Sven J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4790977/
https://ncbi.nlm.nih.gov/pubmed/26903619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522361113
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