טוען...

Adaptive responses to mTOR gene targeting in hematopoietic stem cells reveal a proliferative mechanism evasive to mTOR inhibition

The mechanistic target of rapamycin (mTOR) is a central regulator of cell growth and an attractive anticancer target that integrates diverse signals to control cell proliferation. Previous studies using mTOR inhibitors have shown that mTOR targeting suppresses gene expression and cell proliferation....

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Proc Natl Acad Sci U S A
Main Authors: Fan, Cuiqing, Zhao, Chuntao, Zhang, Feng, Kesarwani, Meenu, Tu, Zhaowei, Cai, Xiongwei, Davis, Ashley Kuenzi, Xu, Lingli, Hochstetler, Cindy L., Chen, Xiaoyi, Guo, Fukun, Huang, Gang, Azam, Mohammad, Tian, Weidong, Lu, Q. Richard, Zheng, Yi
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817152/
https://ncbi.nlm.nih.gov/pubmed/33443202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2020102118
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