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GATA6 is a regulator of sinus node development and heart rhythm

The sinus node (SAN) is the primary pacemaker of the human heart, and abnormalities in its structure or function cause sick sinus syndrome, the most common reason for electronic pacemaker implantation. Here we report that transcription factor GATA6, whose mutations in humans are linked to arrhythmia...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Gharibeh, Lara, Yamak, Abir, Whitcomb, Jamieson, Lu, Aizhu, Joyal, Mathieu, Komati, Hiba, Liang, Wenbin, Fiset, Céline, Nemer, Mona
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817143/
https://ncbi.nlm.nih.gov/pubmed/33443158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007322118
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