GATA6 is a regulator of sinus node development and heart rhythm

The sinus node (SAN) is the primary pacemaker of the human heart, and abnormalities in its structure or function cause sick sinus syndrome, the most common reason for electronic pacemaker implantation. Here we report that transcription factor GATA6, whose mutations in humans are linked to arrhythmia...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Gharibeh, Lara, Yamak, Abir, Whitcomb, Jamieson, Lu, Aizhu, Joyal, Mathieu, Komati, Hiba, Liang, Wenbin, Fiset, Céline, Nemer, Mona
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2021
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817143/
https://ncbi.nlm.nih.gov/pubmed/33443158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2007322118
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