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Cyclin D(2) rescues size and function of GATA4 haplo-insufficient hearts
Transcription factor GATA4 is a key regulator of cardiomyocyte growth, and differentiation and 50% reduction in GATA4 levels results in hypoplastic hearts. Search for GATA4 targets/effectors revealed cyclin D(2) (CD2), a member of the D-type cyclins (D(1), D(2), and D(3)) that play a vital role in c...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Physiological Society
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3469642/ https://ncbi.nlm.nih.gov/pubmed/22923619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00250.2012 |
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