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Tumor infiltrating lymphocyte clusters are associated with response to immune checkpoint inhibition in BRAF V600(E/K) mutated malignant melanomas

Patients with metastasized malignant melanomas (MM) are regularly treated with immune checkpoint inhibitors (CPI). Within our study, we evaluated the predictive value of tumor infiltrating lymphocyte (TIL) clusters in primary MM and its association to molecular subtypes to predict response to CPI tr...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Klein, Sebastian, Mauch, Cornelia, Brinker, Klaus, Noh, Ka-Won, Knez, Sonja, Büttner, Reinhard, Quaas, Alexander, Helbig, Doris
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815914/
https://ncbi.nlm.nih.gov/pubmed/33469107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81330-4
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