Rheumatoid arthritis CD14(+) monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease

INTRODUCTION: This study investigates the metabolic activity of circulating monocytes and their impact on pro‐inflammatory responses in RA and explores whether this phenotype is already primed for inflammation before clinical manifestations of disease. METHODS: Blood was collected and CD14(+) monocy...

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Veröffentlicht in:Clin Transl Immunology
Hauptverfasser: McGarry, Trudy, Hanlon, Megan M., Marzaioli, Viviana, Cunningham, Clare C, Krishna, Vinod, Murray, Kieran, Hurson, Conor, Gallagher, Phil, Nagpal, Sunil, Veale, Douglas J, Fearon, Ursula
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
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Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815439/
https://ncbi.nlm.nih.gov/pubmed/33510894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1237
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