Rheumatoid arthritis CD14(+) monocytes display metabolic and inflammatory dysfunction, a phenotype that precedes clinical manifestation of disease

INTRODUCTION: This study investigates the metabolic activity of circulating monocytes and their impact on pro‐inflammatory responses in RA and explores whether this phenotype is already primed for inflammation before clinical manifestations of disease. METHODS: Blood was collected and CD14(+) monocy...

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Detalhes bibliográficos
Publicado no:Clin Transl Immunology
Main Authors: McGarry, Trudy, Hanlon, Megan M., Marzaioli, Viviana, Cunningham, Clare C, Krishna, Vinod, Murray, Kieran, Hurson, Conor, Gallagher, Phil, Nagpal, Sunil, Veale, Douglas J, Fearon, Ursula
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2021
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7815439/
https://ncbi.nlm.nih.gov/pubmed/33510894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cti2.1237
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