A Bump-Hole Strategy for Increased Stringency of Cell-Specific Metabolic Labeling of RNA

Profiling RNA expression in a cell-specific manner continues to be a grand challenge in biochemical research. Bioorthogonal nucleosides can be utilized to track RNA expression; however, these methods currently have limitations due to background and incorporation of analogs into undesired cells. Here...

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Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Nguyen, Kim, Kubota, Miles, del Arco, Jon, Feng, Chao, Singha, Monika, Beasley, Samantha, Sakr, Jasmine, Gandhi, Sunil P., Blurton-Jones, Matthew, Lucas, Jesus Fernández, Spitale, Robert C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814973/
https://ncbi.nlm.nih.gov/pubmed/33222436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.0c00755
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