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Molecular regulation and function of FoxO3 in chronic kidney disease

PURPOSE OF REVIEW: FOXOs are transcription factors that regulate downstream target genes to counteract to cell stress. Here we review the function and regulation of FOXO transcription factors, the mechanism of FOXO3 activation in the kidney, and the role of FOXO3 in delaying the development of chron...

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Pubblicato in:Curr Opin Nephrol Hypertens
Autore principale: Lin, Fangming
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814875/
https://ncbi.nlm.nih.gov/pubmed/32427691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MNH.0000000000000616
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