FoxO3 activation in hypoxic tubules prevents chronic kidney disease

Acute kidney injury (AKI) can lead to chronic kidney disease (CKD) if injury is severe and/or repair is incomplete. However, the pathogenesis of CKD following renal ischemic injury is not fully understood. Capillary rarefaction and tubular hypoxia are common findings during the AKI-to-CKD transition...

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Bibliografiske detaljer
Udgivet i:J Clin Invest
Main Authors: Li, Ling, Kang, Huimin, Zhang, Qing, D’Agati, Vivette D., Al-Awqati, Qais, Lin, Fangming
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6541430/
https://ncbi.nlm.nih.gov/pubmed/30912765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI122256
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