Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease

The Wnt/β-catenin signaling pathway plays an important role in renal development and is reexpressed in the injured kidney and other organs. β-Catenin signaling is protective in acute kidney injury (AKI) through actions on the proximal tubule, but the current dogma is that Wnt/β-catenin signaling pro...

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Veröffentlicht in:JCI Insight
Hauptverfasser: Nlandu-Khodo, Stellor, Osaki, Yosuke, Scarfe, Lauren, Yang, Haichun, Phillips-Mignemi, Melanie, Tonello, Jane, Saito-Diaz, Kenyi, Neelisetty, Surekha, Ivanova, Alla, Huffstater, Tessa, McMahon, Robert, Taketo, M. Mark, deCaestecker, Mark, Kasinath, Balakuntalam, Harris, Raymond C., Lee, Ethan, Gewin, Leslie S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2020
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259539/
https://ncbi.nlm.nih.gov/pubmed/32369448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.135454
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