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Design, Synthesis, and Study of Lactam and Ring-Expanded Analogues of Teixobactin
This paper describes the chemical synthesis, X-ray crystallographic structure, and antibiotic activity assay of lactam analogues of teixobactin and explores ring-expanded analogues of teixobactin with β(3)-homo amino acids. Lactam analogues of teixobactin containing all four stereoisomers of azathre...
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| Publicado no: | J Org Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7814697/ https://ncbi.nlm.nih.gov/pubmed/31746604 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.9b02631 |
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