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X-ray Crystallographic Structure of a Teixobactin Derivative Reveals Amyloid-Like Assembly

This paper describes the X-ray crystallographic structure of a derivative of the antibiotic teixobactin and shows that its supramolecular assembly through the formation of antiparallel β-sheets creates binding sites for oxyanions. An active derivative of teixobactin containing lysine in place of all...

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Pubblicato in:J Am Chem Soc
Autori principali: Yang, Hyunjun, Wierzbicki, Michał, Bois, Derek R. Du, Nowick, James S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6356018/
https://ncbi.nlm.nih.gov/pubmed/30296063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.8b07709
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