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Two cases of carfilzomib‐induced thrombotic microangiopathy successfully treated with Eculizumab in multiple myeloma

BACKGROUND: Treatment with proteasome inhibitors like carfilzomib in patients with multiple myeloma (MM) can induce thrombotic microangiopathy (TMA) characterized by neurological symptoms, acute kidney injury, hemolysis and thrombocytopenia. Successful treatment with the monoclonal antibody eculizum...

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Detalhes bibliográficos
Publicado no:BMC Nephrol
Main Authors: Rassner, Michael, Baur, Rebecca, Wäsch, Ralph, Schiffer, Mario, Schneider, Johanna, Mackensen, Andreas, Engelhardt, Monika
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2021
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814610/
https://ncbi.nlm.nih.gov/pubmed/33461512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-02226-5
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