Two cases of carfilzomib‐induced thrombotic microangiopathy successfully treated with Eculizumab in multiple myeloma

BACKGROUND: Treatment with proteasome inhibitors like carfilzomib in patients with multiple myeloma (MM) can induce thrombotic microangiopathy (TMA) characterized by neurological symptoms, acute kidney injury, hemolysis and thrombocytopenia. Successful treatment with the monoclonal antibody eculizum...

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Vydáno v:BMC Nephrol
Hlavní autoři: Rassner, Michael, Baur, Rebecca, Wäsch, Ralph, Schiffer, Mario, Schneider, Johanna, Mackensen, Andreas, Engelhardt, Monika
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
Témata:
Case Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814610/
https://ncbi.nlm.nih.gov/pubmed/33461512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-02226-5
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