Two cases of carfilzomib‐induced thrombotic microangiopathy successfully treated with Eculizumab in multiple myeloma

BACKGROUND: Treatment with proteasome inhibitors like carfilzomib in patients with multiple myeloma (MM) can induce thrombotic microangiopathy (TMA) characterized by neurological symptoms, acute kidney injury, hemolysis and thrombocytopenia. Successful treatment with the monoclonal antibody eculizum...

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Bibliografiske detaljer
Udgivet i:BMC Nephrol
Main Authors: Rassner, Michael, Baur, Rebecca, Wäsch, Ralph, Schiffer, Mario, Schneider, Johanna, Mackensen, Andreas, Engelhardt, Monika
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2021
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814610/
https://ncbi.nlm.nih.gov/pubmed/33461512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-02226-5
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