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Two cases of carfilzomib‐induced thrombotic microangiopathy successfully treated with Eculizumab in multiple myeloma

BACKGROUND: Treatment with proteasome inhibitors like carfilzomib in patients with multiple myeloma (MM) can induce thrombotic microangiopathy (TMA) characterized by neurological symptoms, acute kidney injury, hemolysis and thrombocytopenia. Successful treatment with the monoclonal antibody eculizum...

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Dades bibliogràfiques
Publicat a:BMC Nephrol
Autors principals: Rassner, Michael, Baur, Rebecca, Wäsch, Ralph, Schiffer, Mario, Schneider, Johanna, Mackensen, Andreas, Engelhardt, Monika
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814610/
https://ncbi.nlm.nih.gov/pubmed/33461512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12882-020-02226-5
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