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Gene expression regulates metabolite homeostasis during the Crabtree effect: Implications for the adaptation and evolution of Metabolism

A key issue in both molecular and evolutionary biology has been to define the roles of genes and phenotypes in the adaptation of organisms to environmental changes. The dominant view has been that an organism’s metabolic adaptations are driven by gene expression and that gene mutations, independent...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Rothman, Douglas L., Stearns, Stephen C., Shulman, Robert G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814475/
https://ncbi.nlm.nih.gov/pubmed/33372135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014013118
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