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Protein phosphorylation can regulate metabolite concentrations rather than control flux: The example of glycogen synthase

Despite dramatic increases in glucose influx during the transition from fasting to fed states, plasma glucose concentration remains tightly controlled. This constancy is in large part due to the capacity of skeletal muscle to absorb excess glucose and store it as glycogen. The magnitude of this capa...

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Publicado en:Proc Natl Acad Sci U S A
Autores principales: Schafer, James R. A., Fell, David A., Rothman, Douglas, Shulman, Robert G.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2004
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Acceso en línea:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC341749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14745035/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0307299101
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