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Protein phosphorylation can regulate metabolite concentrations rather than control flux: The example of glycogen synthase

Despite dramatic increases in glucose influx during the transition from fasting to fed states, plasma glucose concentration remains tightly controlled. This constancy is in large part due to the capacity of skeletal muscle to absorb excess glucose and store it as glycogen. The magnitude of this capa...

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Bibliographic Details
Main Authors: Schafer, James R. A., Fell, David A., Rothman, Douglas, Shulman, Robert G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC341749/
https://ncbi.nlm.nih.gov/pubmed/14745035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307299101
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