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Gene expression regulates metabolite homeostasis during the Crabtree effect: Implications for the adaptation and evolution of Metabolism

A key issue in both molecular and evolutionary biology has been to define the roles of genes and phenotypes in the adaptation of organisms to environmental changes. The dominant view has been that an organism’s metabolic adaptations are driven by gene expression and that gene mutations, independent...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Rothman, Douglas L., Stearns, Stephen C., Shulman, Robert G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814475/
https://ncbi.nlm.nih.gov/pubmed/33372135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2014013118
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