Analysis of insulin glulisine at the molecular level by X-ray crystallography and biophysical techniques

This study concerns glulisine, a rapid-acting insulin analogue that plays a fundamental role in diabetes management. We have applied a combination of methods namely X-ray crystallography, and biophysical characterisation to provide a detailed insight into the structure and function of glulisine. X-r...

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Publicat a:Sci Rep
Autors principals: Gillis, Richard B., Solomon, Hodaya V., Govada, Lata, Oldham, Neil J., Dinu, Vlad, Jiwani, Shahwar Imran, Gyasi-Antwi, Philemon, Coffey, Frank, Meal, Andy, Morgan, Paul S., Harding, Stephen E., Helliwell, John R., Chayen, Naomi E., Adams, Gary G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2021
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7814034/
https://ncbi.nlm.nih.gov/pubmed/33462295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-021-81251-2
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