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ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4

Macrodomains are proteins that recognize and hydrolyze ADP ribose (ADPR) modifications of intracellular proteins. Macrodomains are implicated in viral genome replication and interference with host cell immune responses. They are important to the infectious cycle of Coronaviridae and Togaviridae viru...

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Bibliografski detalji
Izdano u:Proc Natl Acad Sci U S A
Glavni autori: Hammond, Robert G., Schormann, Norbert, McPherson, Robert Lyle, Leung, Anthony K. L., Deivanayagam, Champion C. S., Johnson, Margaret A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2021
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812796/
https://ncbi.nlm.nih.gov/pubmed/33397718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004500118
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