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ADP-ribose and analogues bound to the deMARylating macrodomain from the bat coronavirus HKU4
Macrodomains are proteins that recognize and hydrolyze ADP ribose (ADPR) modifications of intracellular proteins. Macrodomains are implicated in viral genome replication and interference with host cell immune responses. They are important to the infectious cycle of Coronaviridae and Togaviridae viru...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2021
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7812796/ https://ncbi.nlm.nih.gov/pubmed/33397718 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2004500118 |
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