Discovery of Potent Inhibitors of Streptococcus mutans Biofilm with Antivirulence Activity

[Image: see text] Dental caries is a bacterial infectious disease characterized by demineralization of the tooth enamel. Treatment of this disease with conventional antibiotics is largely ineffective as the cariogenic bacteria form tenacious biofilms that are resistant to such treatments. The main e...

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Veröffentlicht in:ACS Med Chem Lett
Hauptverfasser: Nijampatnam, Bhavitavya, Ahirwar, Parmanand, Pukkanasut, Piyasuda, Womack, Holly, Casals, Luke, Zhang, Hua, Cai, Xia, Michalek, Suzanne M., Wu, Hui, Velu, Sadanandan E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2020
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812604/
https://ncbi.nlm.nih.gov/pubmed/33488963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00373
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