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Discovery of Potent Inhibitors of Streptococcus mutans Biofilm with Antivirulence Activity

[Image: see text] Dental caries is a bacterial infectious disease characterized by demineralization of the tooth enamel. Treatment of this disease with conventional antibiotics is largely ineffective as the cariogenic bacteria form tenacious biofilms that are resistant to such treatments. The main e...

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發表在:ACS Med Chem Lett
Main Authors: Nijampatnam, Bhavitavya, Ahirwar, Parmanand, Pukkanasut, Piyasuda, Womack, Holly, Casals, Luke, Zhang, Hua, Cai, Xia, Michalek, Suzanne M., Wu, Hui, Velu, Sadanandan E.
格式: Artigo
語言:Inglês
出版: American Chemical Society 2020
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812604/
https://ncbi.nlm.nih.gov/pubmed/33488963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00373
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