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Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents

Streptococcus mutans has been implicated as the major etiological agent in the initiation and the development of dental caries due to its robust capacity to form tenacious biofilms. Ideal therapeutics for this disease will aim to selectively inhibit the biofilm formation process while preserving the...

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Détails bibliographiques
Publié dans:Bioorg Med Chem Lett
Auteurs principaux: Nijampatnam, Bhavitavya, Casals, Luke, Zheng, Ruowen, Wu, Hui, Velu, Sadanandan E.
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207028/
https://ncbi.nlm.nih.gov/pubmed/27371109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.06.033
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