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Hydroxychalcone inhibitors of Streptococcus mutans glucosyl transferases and biofilms as potential anticaries agents

Streptococcus mutans has been implicated as the major etiological agent in the initiation and the development of dental caries due to its robust capacity to form tenacious biofilms. Ideal therapeutics for this disease will aim to selectively inhibit the biofilm formation process while preserving the...

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Bibliografiske detaljer
Udgivet i:Bioorg Med Chem Lett
Main Authors: Nijampatnam, Bhavitavya, Casals, Luke, Zheng, Ruowen, Wu, Hui, Velu, Sadanandan E.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207028/
https://ncbi.nlm.nih.gov/pubmed/27371109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.06.033
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