Neddylation inhibitor MLN4924 has anti‐HBV activity via modulating the ERK‐HNF1α‐C/EBPα‐HNF4α axis

Hepatitis B virus (HBV) infection is a major public health problem. The high levels of HBV DNA and HBsAg are positively associated with the development of secondary liver diseases, including hepatocellular carcinoma (HCC). Current treatment with nucleos(t)ide analogues mainly reduces viral DNA, but...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Cell Mol Med
Auteurs principaux: Xie, Mingjie, Guo, Huiting, Lou, Guohua, Yao, Jiping, Liu, Yanning, Sun, Yi, Yang, Zhenggang, Zheng, Min
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7812279/
https://ncbi.nlm.nih.gov/pubmed/33263949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.16137
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