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A Novel Lipofuscin-detecting Marker of Senescence Relates With Hypoxia, Dysregulated Autophagy and With Poor Prognosis in Non-small-cell-lung Cancer

Background/Aim: The role of senescence in defining tumor aggressiveness at a clinical level remains obscure. A novel mixed histochemical/immunohistochemical method (SenTraGor™, STG) detecting lipofuscin accumulation allows the assessment of senescent cells in paraffin-embedded tissue material. Mater...

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Detalhes bibliográficos
Publicado no:In Vivo
Main Authors: GIATROMANOLAKI, ALEXANDRA, KOUROUPI, MARIA, BALASKA, KONSTANTINA, KOUKOURAKIS, MICHAEL I.
Formato: Artigo
Idioma:Inglês
Publicado em: International Institute of Anticancer Research 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811663/
https://ncbi.nlm.nih.gov/pubmed/33144423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/invivo.12154
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