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MTOR-initiated Metabolic Switch and Degeneration in the Retinal Pigment Epithelium
The retinal pigment epithelium (RPE) is a particularly vulnerable tissue to age-dependent degeneration. Over the lifespan, the RPE develops an expanded endo-lysosomal compartment to maintain the high efficiency of phagocytosis and degradation of photoreceptor outer segments (POS) necessary for photo...
Enregistré dans:
| Publié dans: | FASEB J |
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| Auteurs principaux: | , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7811279/ https://ncbi.nlm.nih.gov/pubmed/32721041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.202000612R |
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