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Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment

Regulatory T cells (Tregs) are emerging as a new cell-based therapy in solid organ transplantation. Adoptive transfer of Tregs has been shown preclinically to protect from graft rejection, and the safety of Treg therapy has been demonstrated in clinical trials. Despite these successes, the in vivo d...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Jacob, Jacinta, Nadkarni, Suchita, Volpe, Alessia, Peng, Qi, Tung, Sim L., Hannen, Rosalind F., Mohseni, Yasmin R., Scotta, Cristiano, Marelli-Berg, Federica M., Lechler, Robert I., Smyth, Lesley A., Fruhwirth, Gilbert O., Lombardi, Giovanna
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811063/
https://ncbi.nlm.nih.gov/pubmed/33511246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.12.003
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