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Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment

Regulatory T cells (Tregs) are emerging as a new cell-based therapy in solid organ transplantation. Adoptive transfer of Tregs has been shown preclinically to protect from graft rejection, and the safety of Treg therapy has been demonstrated in clinical trials. Despite these successes, the in vivo d...

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Dades bibliogràfiques
Publicat a:Mol Ther Methods Clin Dev
Autors principals: Jacob, Jacinta, Nadkarni, Suchita, Volpe, Alessia, Peng, Qi, Tung, Sim L., Hannen, Rosalind F., Mohseni, Yasmin R., Scotta, Cristiano, Marelli-Berg, Federica M., Lechler, Robert I., Smyth, Lesley A., Fruhwirth, Gilbert O., Lombardi, Giovanna
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811063/
https://ncbi.nlm.nih.gov/pubmed/33511246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.12.003
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