Spatiotemporal in vivo tracking of polyclonal human regulatory T cells (Tregs) reveals a role for innate immune cells in Treg transplant recruitment

Regulatory T cells (Tregs) are emerging as a new cell-based therapy in solid organ transplantation. Adoptive transfer of Tregs has been shown preclinically to protect from graft rejection, and the safety of Treg therapy has been demonstrated in clinical trials. Despite these successes, the in vivo d...

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Bibliografske podrobnosti
izdano v:Mol Ther Methods Clin Dev
Main Authors: Jacob, Jacinta, Nadkarni, Suchita, Volpe, Alessia, Peng, Qi, Tung, Sim L., Hannen, Rosalind F., Mohseni, Yasmin R., Scotta, Cristiano, Marelli-Berg, Federica M., Lechler, Robert I., Smyth, Lesley A., Fruhwirth, Gilbert O., Lombardi, Giovanna
Format: Artigo
Jezik:Inglês
Izdano: American Society of Gene & Cell Therapy 2020
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7811063/
https://ncbi.nlm.nih.gov/pubmed/33511246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2020.12.003
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